1615138

Sodium trifluoroacetate

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): Sodium trifluoroacetate, Trifluoroacetic acid sodium salt
• Linear Formula: CF₃COONa
• CAS Number: 2923-18-4
• Molecular Weight: 136.01
• Beilstein: 3597949
• MDL number: MFCD00013217
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329751130
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: sodium trifluoroacetate
• 양식: powder
• 제조업체/상표: USP
• mp: 205-207 °C (dec.) (lit.)
• density: 1.49 g/mL (lit.)
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: [Na+].[O-]C(=O)C(F)(F)F
• InChI: 1S/C2HF3O2.Na/c3-2(4,5)1(6)7;/h(H,6,7);/q;+1/p-1
• InChI key: UYCAUPASBSROMS-UHFFFAOYSA-M

설명

일반 설명

Sodium trifluoroacetate (TFA) is a commonly encountered residual reagent or counter-ion in peptide synthesis and purification. It is often present due to the use of trifluoroacetic acid in cleavage and purification steps. The USP standard supports the identification and quantification of TFA in peptide active pharmaceutical ingredients (APIs) and formulations.

The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

애플리케이션

Sodium trifluoroacetate reference standard intended for use in specified quality tests and assays.

Also used to prepare trifluoroacetic acid (TFA) Stock solution to determine the amount of trifluoroacetic acid (TFA) in peptides according to the given below general chapter of United States Pharmacopeia (USP):

• 〈503.1〉 Trifluoroacetic acid (TFA) in peptides

기타 정보

This product is part of the USP Biologics program.

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS09
• 유해 및 위험 성명서: H411
• 예방조치 성명서: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable