107425

Nicotinic hydrazide

97%

• Synonym(s): Nicotinic acid hydrazide
• Empirical Formula (Hill Notation): C₆H₇N₃O
• CAS Number: 553-53-7
• Molecular Weight: 137.14
• Beilstein: 119299
• EC Number: 209-041-0
• MDL number: MFCD00006383
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846769
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• mp: 159-161 °C (lit.)
• solubility: H₂O: soluble 50 mg/mL
• functional group: amine; hydrazine
• SMILES string: NNC(=O)c1cccnc1
• InChI: 1S/C6H7N3O/c7-9-6(10)5-2-1-3-8-4-5/h1-4H,7H2,(H,9,10)
• InChI key: KFUSANSHCADHNJ-UHFFFAOYSA-N

Description

General description

Nicotinic hydrazide is a heterocyclic compound that can be used to synthesize Schiff bases.

Application

Nicotinic hydrazide was used in hydrazone library formation. It was used to study the oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase.

Biochem/physiol Actions

Nicotinic hydrazide is an inhibitor of peroxidase enzyme. It forms solid metal complexes having strong biological activity.

Preparation Note

Nicotinic hydrazide dissolves in water at a concentration of 50 mg/ml to form a clear, colourless solution.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves