108995

Methyl thioglycolate

95%

• Synonym(s): Methyl mercaptoacetate
• Linear Formula: HSCH₂CO₂CH₃
• CAS Number: 2365-48-2
• Molecular Weight: 106.14
• Beilstein: 506259
• EC Number: 219-121-7
• MDL number: MFCD00004873
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846848
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 95%
• reaction suitability: reagent type: ligand; reaction type: [1,2]-Wittig Rearrangement
• refractive index: n20/D 1.466 (lit.)
• bp: 42-43 °C/10 mmHg (lit.)
• density: 1.187 g/mL at 25 °C (lit.)
• functional group: ester; thiol
• SMILES string: COC(=O)CS
• InChI: 1S/C3H6O2S/c1-5-3(4)2-6/h6H,2H2,1H3
• InChI key: MKIJJIMOAABWGF-UHFFFAOYSA-N

Description

General description

Methyl thioglycolate reacts with nonprotein component of the antitumor antibiotic neocarzinostatin to form 1:1 adduct. It reacts with isothiocyanate to form Rhodanine.

Application

Methyl thioglycolate was used in the preparation of:

• 3-carbomethoxy-4- oxotetrahydrothiopyran, 2- and 4-carbomethoxy-3-oxotetrahydrothiophene
• methyl thioglycolate and aminoethanethiol conjugated gold nanorods.

Thiol Organocatalyst used in conjunction with visible light photocatalysis to affect the direct arylation of benzylic ether C-H bonds

A General Strategy for Organocatalytic Activation of C–H Bonds via Photoredox Catalysis: Direct Arylation of Benzylic Ethers

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Safety Information

• Pictograms: GHS02,GHS06
• Signal Word: Danger
• Hazard Statements: H226,H301,H315,H319,H332,H335
• Precautionary Statements: P210 - P233 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 132.8 °F - closed cup
• Flash Point(C): 56 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves