120685

N-Cyclohexylformamide

99%

• Linear Formula: HCONHC₆H₁₁
• CAS Number: 766-93-8
• Molecular Weight: 127.18
• MDL number: MFCD00003828
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847425
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• bp: 113 °C/700 mmHg (lit.)
• mp: 36-41 °C (lit.)
• functional group: amide
• SMILES string: O=CNC1CCCCC1
• InChI: 1S/C7H13NO/c9-6-8-7-4-2-1-3-5-7/h6-7H,1-5H2,(H,8,9)
• InChI key: SWGXDLRCJNEEGZ-UHFFFAOYSA-N
• Gene Information: human ... ADH1A(124), ADH1B(125), ADH1C(126), ADH4(127), ADH7(131), EPHX2(2053) ; mouse ... Ephx2(13850)

Description

General description

N-Cyclohexylformamide binds to the complex of horse liver alcohol dehydrogenase with NADH and is similar to the Michaelis complex for aldehyde reduction catalyzed by the enzyme. It is formed during hydration of cyclohexyl isocyanide catalyzed by a novel enzyme isonitrile hydratase from Pseudomonas putida N19-2 .

Application

N-Cyclohexylformamide was used in the synthesis of 2-methylidene-1,3-selenazolidine derivatives.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318,H335
• Precautionary Statements: P261 - P280 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): >235.4 °F - closed cup
• Flash Point(C): > 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves