125237

4-Chlorothiophenol

97%

• Synonym(s): 4-Chlorobenzenethiol, 4-Chlorophenyl mercaptan
• Linear Formula: ClC₆H₄SH
• CAS Number: 106-54-7
• Molecular Weight: 144.62
• Beilstein: 605971
• EC Number: 203-408-9
• MDL number: MFCD00004847
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847657
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• bp: 205-207 °C (lit.)
• mp: 49-51 °C (lit.)
• solubility: methanol: soluble
• functional group: chloro
• SMILES string: Sc1ccc(Cl)cc1
• InChI: 1S/C6H5ClS/c7-5-1-3-6(8)4-2-5/h1-4,8H
• InChI key: VZXOZSQDJJNBRC-UHFFFAOYSA-N

Description

General description

4-Chlorothiophenol undergoes oxidative coupling catalyzed by iron(III)-tetra phenyl prophyrin to form disulfides.

Application

4-Chlorothiophenol was used to modify poly(vinyl chloride) and to synthesize poly(vinyl chloride) with halogen groups.

Reactant involved in:

• Oxidation to disulfides using cobalt-salen catalysts and air oxidizing agents
• Thiourea-catalyzed sulfa-Michael addition to acryloyloxazolidinones
• Pummerer-type cyclization
• C-H Activation and C-S cross-coupling with heterocycles
• Allylic sulfenylation with allylic carbonates
• Lewis acid-catalyzed electrophilic ring-opening reactions of 2-aryl-3,4-dihydropyrans

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H314
• Precautionary Statements: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves