133507

2-Amino-5-nitrothiazole

97%

• Empirical Formula (Hill Notation): C₃H₃N₃O₂S
• CAS Number: 121-66-4
• Molecular Weight: 145.14
• Beilstein: 126797
• EC Number: 204-490-9
• MDL number: MFCD00005326
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848112
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: solid
• mp: 195-200 °C (dec.) (lit.)
• solubility: 95% ethanol: soluble 1g/150g at 20 °C; diethyl ether: soluble 1g/250g at 20 °C; chloroform: insoluble; water: slightly soluble
• functional group: nitro
• SMILES string: Nc1ncc(s1)[N+]([O-])=O
• InChI: 1S/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5)
• InChI key: MIHADVKEHAFNPG-UHFFFAOYSA-N

Description

General description

2-Amino-5-nitrothiazole(ANT) is a hypoxic radiosensitizing drug. ANT forms square-planar complex, trans-[PdCl₂(ANT)₂] with palladium in methanol.

Application

2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves