133760

trans-Cinnamic acid

97%

• Synonym(s): trans-3-Phenylacrylic acid, Cinnamic acid
• Linear Formula: C₆H₅CH=CHCOOH
• CAS Number: 140-10-3
• Molecular Weight: 148.16
• Beilstein: 1905952
• EC Number: 205-398-1
• MDL number: MFCD00004369
• UNSPSC Code: 12352100
• eCl@ss: 39023931
• PubChem Substance ID: 24848120
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: solid
• bp: 300 °C (lit.)
• mp: 132-135 °C (lit.)
• functional group: carboxylic acid; phenyl
• SMILES string: OC(=O)\C=C\c1ccccc1
• InChI: 1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+
• InChI key: WBYWAXJHAXSJNI-VOTSOKGWSA-N

Description

Application

trans-Cinnamic acid was used to establish library of phenolic compounds by liquid chromatography/ultraviolet and mass spectrometry/mass spectrometry.

Biochem/physiol Actions

trans-cinnamic acid has inhibitory effect on phorbol-12-myristate-13-acetate-induced invasion of human lung adenocarcinoma A549 cells. It is a potential agent which can prevent lung tumor cells from metastasizing. It induces intracellular release of Ca²⁺ from the vacuole to the cytoplasm which triggers phytotoxicity in cucumber.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): 320.0 °F - closed cup
• Flash Point(C): 160 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves