136727

3-Chlorobenzyl bromide

97%

• Synonym(s): α-Bromo-3-chlorotoluene
• Linear Formula: ClC₆H₄CH₂Br
• CAS Number: 766-80-3
• Molecular Weight: 205.48
• Beilstein: 636504
• EC Number: 212-171-0
• MDL number: MFCD00000597
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848293
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: liquid
• refractive index: n20/D 1.588 (lit.)
• bp: 109-110 °C/12 mmHg (lit.)
• density: 1.565 g/mL at 25 °C (lit.)
• functional group: bromo; chloro
• SMILES string: Clc1cccc(CBr)c1
• InChI: 1S/C7H6BrCl/c8-5-6-2-1-3-7(9)4-6/h1-4H,5H2
• InChI key: LZIYAIRGDHSVED-UHFFFAOYSA-N

Description

General description

3-Chlorobenzyl bromide reacts with aminoethanol and NaH to yield aminoethyl 3-chlorobenzyl ether.

Application

3-Chlorobenzyl bromide was used in the synthesis of symmetrical and unsymmetrical benzyl thioethers. It was used as starting reagent during the synthesis of 1-(3-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole dihydrochloride.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves