137030

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate

99%

• Synonym(s): 3,5-Dicarbethoxy-1,4-dihydrocollidine, DDC
• Empirical Formula (Hill Notation): C₁₄H₂₁NO₄
• CAS Number: 632-93-9
• Molecular Weight: 267.32
• EC Number: 211-188-0
• MDL number: MFCD00005950
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848309
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: powder
• mp: 130-132 °C (lit.)
• SMILES string: CCOC(=O)C1=C(C)NC(C)=C(C1C)C(=O)OCC
• InChI: 1S/C14H21NO4/c1-6-18-13(16)11-8(3)12(14(17)19-7-2)10(5)15-9(11)4/h8,15H,6-7H2,1-5H3
• InChI key: CDVAIHNNWWJFJW-UHFFFAOYSA-N

Description

Application

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate was used to induce Mallory-Denk body formation in mice in vivo.

Biochem/physiol Actions

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate blocks the heme synthesis and prevents the induction of hepatic heme oxygenase-1 in mice.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves