143073

Diglycolic acid

98%

• Synonym(s): 2,2′-Oxydiacetic acid
• Linear Formula: O(CH₂COOH)₂
• CAS Number: 110-99-6
• Molecular Weight: 134.09
• Beilstein: 1072117
• EC Number: 203-823-5
• MDL number: MFCD00004309
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848573
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 98%
• mp: 140-144 °C (lit.)
• solubility: ethanol: soluble 5%, clear to slightly hazy, colorless to greenish-yellow
• functional group: carboxylic acid; ether
• SMILES string: OC(=O)COCC(O)=O
• InChI: 1S/C4H6O5/c5-3(6)1-9-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
• InChI key: QEVGZEDELICMKH-UHFFFAOYSA-N

Description

General description

Diglycolic acid is a toxic metabolite of diethylene glycol (DEG) responsible for DEG-induced proximal tubular necrosis.

Application

Diglycolic acid was used in the preparation of needle-like aragonite particles from calcium nitrate aqueous solutions.

Biochem/physiol Actions

Diglycolic acid has antithrombogenic properties and induces vasodilation. It inhibits succinate dehydrogenase activity in human proximal tubule cells.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves