145963

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

98%

• Empirical Formula (Hill Notation): C₈H₉ClN₂O₂S
• CAS Number: 5909-24-0
• Molecular Weight: 232.69
• EC Number: 227-619-0
• MDL number: MFCD00006085
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848754
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: powder
• mp: 60-63 °C (lit.)
• functional group: chloro; ester; thioether
• storage temp.: 2-8°C
• SMILES string: CCOC(=O)c1cnc(SC)nc1Cl
• InChI: 1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3
• InChI key: SNNHLSHDDGJVDM-UHFFFAOYSA-N

Description

Application

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate was used in the synthesis of pyrimidinopyridones, potential inhibitors of the FMS tyrosine kinase.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves