157910

Methyl bromoacetate

97%

• Synonym(s): 2-Bromoacetic acid methyl ester, Bromoacetic acid methyl ester, Carbomethoxymethyl bromide, Methyl α-bromoacetate, Methyl 2-bromoacetate, Methyl 2-bromoethanoate
• Linear Formula: BrCH₂COOCH₃
• CAS Number: 96-32-2
• Molecular Weight: 152.97
• Beilstein: 506256
• EC Number: 202-499-2
• MDL number: MFCD00000189
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849708
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: liquid
• refractive index: n20/D 1.458 (lit.)
• bp: 51-52 °C/15 mmHg (lit.)
• density: 1.616 g/mL at 25 °C (lit.)
• functional group: bromo; ester
• SMILES string: COC(=O)CBr
• InChI: 1S/C3H5BrO2/c1-6-3(5)2-4/h2H2,1H3
• InChI key: YDCHPLOFQATIDS-UHFFFAOYSA-N

Description

General description

Methyl bromoacetate is an α-bromo ester. Reactions of the methyl bromoacetate with conjugate base of (methylmethoxycarbene)pentacarbonylchromium(0) yields alkylated carbene complexes.

Application

Methyl bromoacetate was used in the synthesis of novel coumarins. It was also employed in the synthesis of cis-cyclopropanes.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H314,H317
• Precautionary Statements: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1C - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 147.2 °F - closed cup
• Flash Point(C): 64 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves