162906

2-Hydroxy-5-nitrobenzyl bromide

90%

• Synonym(s): α-Bromo-4-nitro-o-cresol, 2-Bromomethyl-4-nitrophenol, Koshland I, Koshland’s Reagent I
• Linear Formula: HOC₆H₃(NO₂)CH₂Br
• CAS Number: 772-33-8
• Molecular Weight: 232.03
• Beilstein: 1868798
• EC Number: 212-248-9
• MDL number: MFCD00007340
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850013
• NACRES: NA.22

Properties

• Assay: 90%
• form: solid
• mp: 144-149 °C (lit.)
• solubility: chloroform: soluble 25 mg/mL, clear, yellow
• functional group: bromo; nitro
• storage temp.: 2-8°C
• SMILES string: Oc1ccc(cc1CBr)[N+]([O-])=O
• InChI: 1S/C7H6BrNO3/c8-4-5-3-6(9(11)12)1-2-7(5)10/h1-3,10H,4H2
• InChI key: KFDPCYZHENQOBV-UHFFFAOYSA-N

Description

General description

2-Hydroxy-5-nitrobenzyl bromide is a protein modifying reagent.

Application

2-Hydroxy-5-nitrobenzyl bromide was used in covalent modification of tryptophan and tryptophan residues in monoclonal immunoglobulin. It was also used as reagent for sulfhydryl modification

Other Notes

Contains 2-hydroxy-5-nitrobenzyl alcohol

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves