168696

4-Hydroxy-1-methyl-2(1H)-quinolone

98%

• Empirical Formula (Hill Notation): C₁₀H₉NO₂
• CAS Number: 1677-46-9
• Molecular Weight: 175.18
• EC Number: 216-830-3
• MDL number: MFCD00024052
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850250
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: powder
• mp: 269-271 °C (lit.)
• SMILES string: CN1C(=O)C=C(O)c2ccccc12
• InChI: 1S/C10H9NO2/c1-11-8-5-3-2-4-7(8)9(12)6-10(11)13/h2-6,12H,1H3
• InChI key: RTNPPPQVXREFKX-UHFFFAOYSA-N

Description

Application

4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones. It was used in the synthesis of :

• 3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone
• 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one
• 3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one
• 3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves