183709

2′-Chloroacetophenone

97%

• Linear Formula: ClC₆H₄COCH₃
• CAS Number: 2142-68-9
• Molecular Weight: 154.59
• Beilstein: 1858916
• EC Number: 218-397-6
• MDL number: MFCD00000560
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851071
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: liquid
• bp: 227-230 °C
• density: 1.190 g/mL at 20 °C
• functional group: chloro; ketone
• SMILES string: CC(=O)c1ccccc1Cl
• InChI: 1S/C8H7ClO/c1-6(10)7-4-2-3-5-8(7)9/h2-5H,1H3
• InChI key: ZDOYHCIRUPHUHN-UHFFFAOYSA-N

Description

General description

2′-Chloroacetophenone undergoes stereoselective reduction to (R)-2′-chloro-1-phenyl-ethanol by Saccharomyces cerevisiae B5. It is commonly used as lacrimator.

Application

2′-Chloroacetophenone was employed as model substrate to investigate the enzymatic performance of Aspergillus terreus and Rhizopus oryzae in enantioselective bioreductions using glycerol as a co-solvent.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 190.4 °F
• Flash Point(C): 88 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves