194387

2-Chlorobenzophenone

≥99%

• Linear Formula: ClC₆H₄COC₆H₅
• CAS Number: 5162-03-8
• Molecular Weight: 216.66
• EC Number: 225-936-9
• MDL number: MFCD00000558
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851648
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥99%
• bp: 330 °C (lit.)
• mp: 44-47 °C (lit.)
• functional group: chloro; ketone; phenyl
• SMILES string: Clc1ccccc1C(=O)c2ccccc2
• InChI: 1S/C13H9ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9H
• InChI key: VMHYWKBKHMYRNF-UHFFFAOYSA-N

Description

General description

Thermodynamics of formation of inclusion complex between 2-chlorobenzophenone and cyclomaltoheptaose (β-cyclodextrin) has been investigated by UV-vis spectroscopy and reversed-phase liquid chromatography. 2-Chlorobenzophenone undergoes reduction in the presence of LiAlH₄ and (R)-(-)-2-(2-iso-indolinyl)butan-1-ol to afford the corresponding benzhydrols.

Application

2-Chlorobenzophenone was used in the synthesis of 1-(2-chlorophenyl)isoquinolin-3-yl trifluoromethanesulfonate.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves