195421

10,11-Dihydrocarbamazepine

99%

• Synonym(s): 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• Empirical Formula (Hill Notation): C₁₅H₁₄N₂O
• CAS Number: 3564-73-6
• Molecular Weight: 238.28
• EC Number: 222-649-0
• MDL number: MFCD00005072
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851693
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• mp: 205-210 °C (lit.)
• solubility: dichloromethane: soluble 2.5%, clear, colorless
• functional group: amine
• SMILES string: NC(=O)N1c2ccccc2CCc3ccccc13
• InChI: 1S/C15H14N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-8H,9-10H2,(H2,16,18)
• InChI key: PHNLCHMJDSSPDQ-UHFFFAOYSA-N

Description

General description

10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.

Application

10,11-Dihydrocarbamazepine was used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It was used in chemiluminescence method for determination of carbamazepine.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H317,H336,H360D
• Precautionary Statements: P201 - P280 - P301 + P312 + P330 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1A - Skin Sens. 1A - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable