220027

3-Indolepropionic acid

ReagentPlus^®, 99%

• Synonym(s): 3-(3-Indolyl)propanoic acid, IPA, Indole-3-propionic acid, NSC 3252, NSC 47831
• Empirical Formula (Hill Notation): C₁₁H₁₁NO₂
• CAS Number: 830-96-6
• Molecular Weight: 189.21
• Beilstein: 147733
• EC Number: 212-600-1
• MDL number: MFCD00005660
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853161
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: ReagentPlus^®
• Assay: 99%
• form: powder
• mp: 134-135 °C (lit.)
• solubility: ethanol: soluble 50 mg/mL, clear, yellow to orange
• functional group: carboxylic acid
• SMILES string: OC(=O)CCc1c[nH]c2ccccc12
• InChI: 1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)
• InChI key: GOLXRNDWAUTYKT-UHFFFAOYSA-N

Description

General description

3-Indolepropionic acid is an effective inhibitor of aggregation of misfolded β-amyloid protein (Abeta). Three-component one-pot procedure has been reported to assemble 3-indolepropionic acids.

Application

Reactant for preparation of:

• Fluorescent analogues of strigolactones
• Anti-tumor agents
• Melanocortin receptors ligands
• Immunosuppressive agents
• Iinhibitors of hepatitis C virus
• Histamine H4 receptor agonists
• NR2B/NMDA receptor antagonists
• CB1 Antagonist for the treatment of obesity
• Antibacterial agents
• Inhibitor of TGF-β receptor binding

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves