247979

1-Bromo-2,4,5-trifluorobenzene

99%

• Linear Formula: BrC₆H₂F₃
• CAS Number: 327-52-6
• Molecular Weight: 210.98
• EC Number: 206-318-8
• MDL number: MFCD00000306
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854904
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: liquid
• refractive index: n20/D 1.485 (lit.)
• bp: 144 °C (lit.)
• mp: −19 °C (lit.)
• solubility: water: insoluble
• density: 1.802 g/mL at 25 °C (lit.)
• functional group: bromo; fluoro
• SMILES string: Fc1cc(F)c(Br)cc1F
• InChI: 1S/C6H2BrF3/c7-3-1-5(9)6(10)2-4(3)8/h1-2H
• InChI key: DVTULTINXNWGJY-UHFFFAOYSA-N

Description

General description

1-Bromo-2,4,5-trifluorobenzene undergoes Br-Mg-exchange reaction with i-PrMgBr in THF to yield organomagnesium compound.

Application

1-Bromo-2,4,5-trifluorobenzene has been used in the synthesis of:

• 3-ethenyl, 3-ethynyl, 3-aryl and 3-cyclopropyl-2,4,5-trifluorobenzoic acids
• 3-bromo-2,5,6-trifluorobenzoic acid and 2,4,5-trifluorobenzoic acid

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 132.8 °F - closed cup
• Flash Point(C): 56 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves