270784

4-(Chloromethyl)benzoyl chloride

97%

• Linear Formula: ClCH₂C₆H₄COCl
• CAS Number: 876-08-4
• Molecular Weight: 189.04
• EC Number: 212-881-0
• MDL number: MFCD00053224
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856399
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• bp: 126-128 °C/6 mmHg (lit.)
• mp: 30-32 °C (lit.)
• functional group: acyl chloride; chloro
• SMILES string: ClCc1ccc(cc1)C(Cl)=O
• InChI: 1S/C8H6Cl2O/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5H2
• InChI key: RCOVTJVRTZGSBP-UHFFFAOYSA-N

Description

Application

4-(Chloromethyl)benzoyl chloride was used as an atom transfer radical polymerization (ATRP) initiator in the growth of polyacrylamide (PAAm) brushes from silicon wafers. It was also used as a building block in a microwave-assisted, solid-phase synthesis of imatinib, an anticancer agent.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H314,H335
• Precautionary Statements: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 199.4 °F - closed cup
• Flash Point(C): 93 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves