277460

3-(Methylthio)propionaldehyde

96%

• Synonym(s): 3-(Methylmercapto)propionaldehyde, 3-(Methylthio)propanal, Methional, NSC 15874
• Linear Formula: CH₃SCH₂CH₂CHO
• CAS Number: 3268-49-3
• Molecular Weight: 104.17
• Beilstein: 1739289
• EC Number: 221-882-5
• MDL number: MFCD00007022
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856764
• NACRES: NA.22

Properties

• vapor density: >1 (vs air)
• Quality Level: 100
• vapor pressure: 760 mmHg ( 165 °C)
• Assay: 96%
• form: liquid
• refractive index: n20/D 1.483 (lit.)
• bp: 165-166 °C (lit.)
• density: 1.043 g/mL at 25 °C (lit.)
• functional group: aldehyde; thioether
• storage temp.: 2-8°C
• SMILES string: CSCCC=O
• InChI: 1S/C4H8OS/c1-6-4-2-3-5/h3H,2,4H2,1H3
• InChI key: CLUWOWRTHNNBBU-UHFFFAOYSA-N

Description

General description

3-(Methylthio)propionaldehyde (methional) is the major product of chemical methionine conversion via Strecker degradation in food.

Application

3-(Methylthio)propionaldehyde has been used as a reactant in:

• Oxidative coupling and chemoselective oxidation
• Intermolecular alkyne hydroacylation reactions
• Oxidation of sulfides to sulfoxides

It can also be used as a biosynthetic precursor of ethylene.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H302 + H332,H311,H315,H317,H318,H412
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point(F): 165.2 °F - closed cup
• Flash Point(C): 74 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves