284262

Iodoacetic anhydride

• Synonym(s): 2-Iodoacetic anhydride, 2-Iodoacetyl 2-iodoacetate, Iodoacetic acid anhydride, Iodoacetyl anhydride
• Linear Formula: (ICH₂CO)₂O
• CAS Number: 54907-61-8
• Molecular Weight: 353.88
• Beilstein: 1812140
• MDL number: MFCD00001080
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857144
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• mp: 47-49 °C (lit.)
• solubility: chloroform: soluble 10%, clear to slightly hazy, yellow (pink or tan)
• functional group: anhydride; ester; iodo
• storage temp.: 2-8°C
• SMILES string: ICC(=O)OC(=O)CI
• InChI: 1S/C4H4I2O3/c5-1-3(7)9-4(8)2-6/h1-2H2
• InChI key: RBNSZWOCWHGHMR-UHFFFAOYSA-N

Description

Application

Reagent used as linker for development of reagents used for differential protein quantitation via ion scanning

Reactant used for:

• Sythesis of N-iodoacetyl glycosylamine derivatives and converting amino precursors to IA derivatives
• Linking lysine residues to N-terminal α-amino groups of peptides
• Capping amines and yielding a thiol reactive iodo-derivative
• Iodoacetylation

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves