293768

1-Methyluracil

99%

• Synonym(s): 1-Methyl-2,4(1H,3H)-pyrimidinedione
• Empirical Formula (Hill Notation): C₅H₆N₂O₂
• CAS Number: 615-77-0
• Molecular Weight: 126.11
• MDL number: MFCD00038666
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857675
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 99%
• mp: 236-238 °C (lit.)
• solubility: 1 M NaOH: soluble 50 mg/mL, clear, colorless
• SMILES string: CN1C=CC(=O)NC1=O
• InChI: 1S/C5H6N2O2/c1-7-3-2-4(8)6-5(7)9/h2-3H,1H3,(H,6,8,9)
• InChI key: XBCXJKGHPABGSD-UHFFFAOYSA-N

Description

General description

1-Methyluracil is of special importance in biochemistry, since uracil attaches ribose in ribonucleic acid (RNA) just precisely at the N1 atom. H-bond complex formation between 1-methyluracil and glycine has been investigated by theoretical calculations and FT-IR spectroscopy in Ar matrices. It forms 1:1 complexes with 9-ethyl-8-bromo-2,6-diaminopurine and the complex structure has been determined by three-dimensional X-ray diffraction methods.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H351
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves