328464

2-Azetidinone

98%

• Synonym(s): β-Propiolactam, 2-Azacyclobutanone
• Empirical Formula (Hill Notation): C₃H₅NO
• CAS Number: 930-21-2
• Molecular Weight: 71.08
• Beilstein: 104563
• MDL number: MFCD00013328
• UNSPSC Code: 12352100
• PubChem Substance ID: 24859374
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• bp: 106 °C/15 mmHg (lit.)
• mp: 74-76 °C (lit.)
• solubility: chloroform: very soluble(lit.); ethanol: very slightly soluble(lit.); water: very soluble(lit.)
• storage temp.: 2-8°C
• SMILES string: O=C1CCN1
• InChI: 1S/C3H5NO/c5-3-1-2-4-3/h1-2H2,(H,4,5)
• InChI key: MNFORVFSTILPAW-UHFFFAOYSA-N

Description

General description

2-Azetidinone is an unsubstituted four membered lactam. 2-Azetidinone is the fundamental building block of β-lactam antibiotics. X-ray photoelectron spectra of 2-azetidinone was investigated. 2-Azetidinone undergoes hydrolysis with aqueous alkali to yield β-alanine.

Application

2-Azetidinone was used in synthesis of optically pure densely functionalized γ-lactams.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves