340928

1,4-Anhydroerythritol

95%

• Synonym(s): (3R,4S)-Tetrahydro-3,4-furandiol, Erythritol-1,4-anhydride, cis-3,4-Dihydroxytetrahydrofuran, cis-Tetrahydrofuran-3,4-diol, meso-3,4-Dihydroxytetrahydrofuran, rel-(3R,4S)-Tetrahydro-3,4-furandiol
• Empirical Formula (Hill Notation): C₄H₈O₃
• CAS Number: 4358-64-9
• Molecular Weight: 104.10
• EC Number: 224-433-1
• MDL number: MFCD00075210
• UNSPSC Code: 12352100
• PubChem Substance ID: 24860877
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 95%
• form: liquid
• refractive index: n20/D 1.477 (lit.)
• density: 1.27 g/mL at 25 °C (lit.)
• functional group: ether; hydroxyl
• SMILES string: O[C@H]1COC[C@H]1O
• InChI: 1S/C4H8O3/c5-3-1-7-2-4(3)6/h3-6H,1-2H2/t3-,4+
• InChI key: SSYDTHANSGMJTP-ZXZARUISSA-N

Description

General description

1,4-Anhydroerythritol is a cyclic vicinal diol. 1,4-Anhydroerythritol undergoes hydrodeoxygenation over tungsten oxide-palladium catalysts to yield 3-hydroxytetrahydrofuran.

Application

1,4-Anhydroerythritol was employed in a key step in the synthesis of glucopyranoside-based analogs of adenophostin A lacking the adenine component.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves