360139

5′-O-(4,4′-Dimethoxytrityl)thymidine

98%

• Synonym(s): DMT-T
• Empirical Formula (Hill Notation): C₃₁H₃₂N₂O₇
• CAS Number: 40615-39-2
• Molecular Weight: 544.59
• Beilstein: 599297
• EC Number: 255-003-1
• MDL number: MFCD00010113
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862149
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• mp: 114-116 °C (subl.) (lit.)
• functional group: ether; hydroxyl; phenyl
• storage temp.: 2-8°C
• SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2O)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5
• InChI: 1S/C31H32N2O7/c1-20-18-33(30(36)32-29(20)35)28-17-26(34)27(40-28)19-39-31(21-7-5-4-6-8-21,22-9-13-24(37-2)14-10-22)23-11-15-25(38-3)16-12-23/h4-16,18,26-28,34H,17,19H2,1-3H3,(H,32,35,36)/t26-,27+,28+/m0/s1
• InChI key: UBTJZUKVKGZHAD-UPRLRBBYSA-N

Description

General description

5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.

Application

5′-O-(4,4′-Dimethoxytrityl)thymidine may be used in the stereoselective synthesis of 3′-deoxy-3′-threo-hydroxymethyl nucleoside, which can be subsequently incorporated into oligodeoxynucleotides. It may be used as research tool for antiviral and anticancer studies.

Safety Information

• Hazard Statements: H413
• Precautionary Statements: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves