374822

4-Bromopyrazole

99%

• Empirical Formula (Hill Notation): C₃H₃BrN₂
• CAS Number: 2075-45-8
• Molecular Weight: 146.97
• MDL number: MFCD00075602
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863341
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• bp: 250-260 °C (lit.)
• mp: 93-96 °C (lit.)
• functional group: bromo
• SMILES string: Brc1cn[nH]c1
• InChI: 1S/C3H3BrN2/c4-3-1-5-6-2-3/h1-2H,(H,5,6)
• InChI key: WVGCPEDBFHEHEZ-UHFFFAOYSA-N

Description

General description

4-Bromopyrazole is a heteroaryl halide and its cyanation in the presence of palladium catalysts has been reported.

4-Bromopyrazole is a pyrazole derivative. It is reported to react with titanium tetrachloride to afford binary adducts. Mutagenicity of 4-bromopyrazole has been tested using the L-arabinose forward mutation assay of Salmonella typhimurium. It is reported to inhibit the oxidative phosphorylation, the ATP^-32P exchange reaction, and energy dependent and independent calcium uptake.

Application

4-Bromopyrazole may be used in the preparation of 4-bromo-1-(2-chloroethyl)-1H-pyrazole. It may be used as starting material in the synthesis of 1,4′-bipyrazoles.

4-Bromopyrazole may be used in the preparation of solid hexacoordinate complexes by reaction with dimethyl- and divinyl-tindichloride.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves