379115

DCC

1.0 M in methylene chloride, for peptide synthesis

• Synonym(s): N,N′-Dicyclohexylcarbodiimide solution
• Linear Formula: C₆H₁₁N=C=NC₆H₁₁
• CAS Number: 538-75-0
• Molecular Weight: 206.33
• MDL number: MFCD00011659
• UNSPSC Code: 12352111
• PubChem Substance ID: 24863614
• NACRES: NA.22

Properties

• Product Name: DCC, 1.0 M in methylene chloride
• form: liquid
• Quality Level: 200
• reaction suitability: reaction type: Coupling Reactions
• concentration: 1.0 M in methylene chloride
• density: 1.247 g/mL at 25 °C
• application(s): peptide synthesis
• SMILES string: C1CCC(CC1)N=C=NC2CCCCC2
• InChI: 1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2
• InChI key: QOSSAOTZNIDXMA-UHFFFAOYSA-N
• Gene Information: human ... EPHX2(2053) ; mouse ... Ephx2(13850)

Description

Application

DCC (N,N′-Dicyclohexylcarbodiimide) is mainly used to mediate peptide coupling and also to activate carboxylic acids for esterification.

Safety Information

• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H312,H315,H317,H318,H336,H351
• Precautionary Statements: P202 - P261 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves