393533

3-(2-Hydroxyphenyl)propionic acid

99%

• Linear Formula: HOC₆H₄CH₂CH₂CO₂H
• CAS Number: 495-78-3
• Molecular Weight: 166.17
• MDL number: MFCD00014026
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864523
• NACRES: NA.22

Properties

• Assay: 99%
• mp: 86-89 °C (lit.)
• functional group: carboxylic acid
• SMILES string: OC(=O)CCc1ccccc1O
• InChI: 1S/C9H10O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-4,10H,5-6H2,(H,11,12)
• InChI key: CJBDUOMQLFKVQC-UHFFFAOYSA-N

Description

General description

3-(2-Hydroxyphenyl) propionic acid is a phenyl propionic acid derivative. It was found to be one of the constituents of Justicia pectoralis Jacq. extract which was analyzed by gas chromatography/mass spectrometry (GC/MS). The antiulcerogenic effect of 3-(2-hydroxyphenyl) propionic acid in the prevention of serotonin-induced ulcerogenesis has been studied in rats. It has been reported to be one of the major microbial metabolite of both (+)-catechin and (-)-epicatechin by human faecal microbiota. Crystal structure study reveals that 3-(2-hydroxyphenyl)propionic acid crystals are monoclinic with space group P2₁/c.

Application

3-(2-Hydroxyphenyl)propionic acid is suitable as a growth substrate for various strains of E. coli and as a standard in the study of microbial metabolism of catechin stereoisomers.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves