437948

2-Chloro-1,1,1-trimethoxyethane

97%

• Synonym(s): Trimethyl chloro-orthoacetate
• Linear Formula: ClCH₂C(OCH₃)₃
• CAS Number: 74974-54-2
• Molecular Weight: 154.59
• MDL number: MFCD00216629
• UNSPSC Code: 12352100
• PubChem Substance ID: 24867410
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• refractive index: n20/D 1.425 (lit.)
• bp: 138 °C (lit.)
• density: 1.147 g/mL at 25 °C (lit.)
• functional group: chloro; ether
• SMILES string: COC(CCl)(OC)OC
• InChI: 1S/C5H11ClO3/c1-7-5(4-6,8-2)9-3/h4H2,1-3H3
• InChI key: NPEIUNVTLXEOLT-UHFFFAOYSA-N

Description

General description

2-Chloro-1,1,1-trimethoxyethane is a chloromethyl heterocyclic compound. It participates in the synthesis of 2-phenyl-1,3,4-oxadiazole derivatives.

Application

2-Chloro-1,1,1-trimethoxyethane may be used for the synthesis of chlorotriazolinone, an NK₁ antagonist and 2-chloromethyl-7-[3-(trifluoromethyl)pyridin-2-yl]-3H-quinazolin-4-one.

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Statements: H226
• Hazard Classifications: Flam. Liq. 3
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 109.4 °F - closed cup
• Flash Point(C): 43 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves