445134

2-Hydroxyacetophenone

98%

• Linear Formula: C₆H₅COCH₂OH
• CAS Number: 582-24-1
• Molecular Weight: 136.15
• EC Number: 209-480-8
• MDL number: MFCD00041829
• UNSPSC Code: 12352100
• PubChem Substance ID: 24868161
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• mp: 86-89 °C (lit.)
• functional group: hydroxyl; ketone; phenyl
• SMILES string: OCC(=O)c1ccccc1
• InChI: 1S/C8H8O2/c9-6-8(10)7-4-2-1-3-5-7/h1-5,9H,6H2
• InChI key: ZWVHTXAYIKBMEE-UHFFFAOYSA-N

Description

Application

2-Hydroxyacetophenone can be used as a starting material for the synthesis of:

• Enantioselective 1R-phenyl-1,2-ethanediol in the presence of a rhodium(III) catalyst by asymmetric transfer hydrogenation.
• Copper(II) complexes of 2-hydroxyacetophenone N-substituted thiosemicarbazones.
• Chromium, molybdenum, and ruthenium complexes of 2-hydroxyacetophenone Schiff bases.
• 2-Hydroxyacetophenone-aroyl hydrazone derivatives for inhibition of copper corrosion in nitric acid.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves