471429

(S)-(−)-α-Amino-γ-butyrolactone hydrobromide

99%

• Synonym(s): L-Homoserine lactone hydrobromide
• Empirical Formula (Hill Notation): C₄H₇NO₂ · HBr
• CAS Number: 15295-77-9
• Molecular Weight: 182.02
• Beilstein: 3912375
• MDL number: MFCD00674493
• UNSPSC Code: 12352005
• PubChem Substance ID: 24870732
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• optical activity: [α]20/D −21°, c = 1 in H₂O
• mp: 225 °C (dec.) (lit.)
• functional group: ester
• storage temp.: 2-8°C
• SMILES string: Br[H].N[C@H]1CCOC1=O
• InChI: 1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
• InChI key: MKLNTBLOABOJFZ-DFWYDOINSA-N

Description

Application

(S)-(-)-α-Amino-γ-butyrolactone hydrobromide may be used as a building block to prepare:

• β-ketoamide N-acylated-L-homoserine lactones (AHLs) as quorum sensing molecules
• p-coumaroyl-HSL (homoserine lactone)
• calpain and lipid peroxidation inhibitors

Used to prepare pseudopeptide inhibitors for Ras farnesyl-protein transferase as well as selenomethionine.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves