498521

3-Ethoxy-3-oxopropylzinc bromide solution

0.5 M in THF

• Synonym(s): (2-Ethoxycarbonylethyl)zinc bromide, (3-Ethoxy-3-oxopropyl)zinc(II)bromide, 3-Ethoxy-3-oxopropylzinc bromide
• Linear Formula: C₂H₅O₂CCH₂CH₂ZnBr
• CAS Number: 193065-68-8
• Molecular Weight: 246.42
• MDL number: MFCD00671976
• UNSPSC Code: 12352103
• PubChem Substance ID: 24873205
• NACRES: NA.22

Properties

• Quality Level: 100
• concentration: 0.5 M in THF
• density: 0.972 g/mL at 25 °C
• functional group: ester
• storage temp.: 2-8°C
• SMILES string: CCOC(=O)CC[Zn]Br
• InChI: 1S/C5H9O2.BrH.Zn/c1-3-5(6)7-4-2;;/h1,3-4H2,2H3;1H;/q;;+1/p-1
• InChI key: XLKAROLEWCMBDC-UHFFFAOYSA-M

Description

Application

3-Ethoxy-3-oxopropylzinc bromide is a reagent used to insert ethyl propanoate group to the substrate. It can be used in:

• Synthesis of γ-keto esters from aryl chlorides.
• Synthesis of sulfones from 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO) and alkyl halides.
• Negishi cross-couplings with aryl vinyl phosphates to synthesize 1,1-disubstituted alkenes.

Legal Information

Product of Rieke Metals, Inc.
Rieke is a registered trademark of Rieke Metals, Inc.

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H314,H335,H351
• Precautionary Statements: P210 - P260 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 1.4 °F - closed cup
• Flash Point(C): -17.0 °C - closed cup