635936

N-Cyclohexylhydroxylamine

• Synonym(s): N-Hydroxycyclohexanamine, N-Hydroxycyclohexylamine
• Linear Formula: C₆H₁₁NHOH
• CAS Number: 2211-64-5
• Molecular Weight: 115.17
• EC Number: 218-650-0
• MDL number: MFCD00021287
• UNSPSC Code: 12352100
• PubChem Substance ID: 24882743
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• mp: 139-140 °C (lit.)
• storage temp.: −20°C
• SMILES string: ONC1CCCCC1
• InChI: 1S/C6H13NO/c8-7-6-4-2-1-3-5-6/h6-8H,1-5H2
• InChI key: GUQRKZPMVLRXLT-UHFFFAOYSA-N

Description

General description

N-Cyclohexylhydroxylamine is formed as one of the by-products during the hydrogenation of nitrocyclohexane to the corresponding cyclohexanone oxime catalyzed by palladium/carbon nanotubes.

Application

Reactant for:

• Aldehyde-catalyzed intermolecular hydroamination
• Condensation reactions
• Preparation of cyclin-dependent kinase inhibitors selective for multiple cyclin-dependent kinases for potential use as antitumor agents
• Preparation of hydroxyurea derivatives as small molecule bradykinin B1 receptor antagonists

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H318
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves