802379

Trifluoromethylation in a Box

• UNSPSC Code: 12352300

Properties

• storage temp.: 2-8°C
• Quality Level: 100

Description

Application

This second-generation kit contains the reagents, catalyst, and solvent required to perform a trifluoromethylation reaction in TPGS-750-M, a surfactant developed by the Lipshutz group as a greener alternative to organic solvents. This technology allows common metal-catalyzed reactions to be run under aqueous conditions, considerably reducing solvent waste. The components are pre-weighed in the appropriate amounts for a 0.5mmol scale reaction.

Please refer to the attached Protocol for details.

Other Notes

Technology Spotlight: Second-Generation, Designer-Surfactant Kits: Solvent-Free, Aqueous Reactions in a Box
Transition-Metal-Catalyzed Cross-Couplings Going Green: in Water at Room Temperature
"Designer"-Surfactant-Enabled Cross-Couplings in Water at Room Temperature
Green Chemistry in the Introductory Organic Laboratory

Safety Information

• Pictograms: GHS02,GHS06,GHS08,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H226,H242,H302,H311,H314,H317,H330,H335,H341,H411
• Precautionary Statements: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Org. Perox. F - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• Flash Point(F): 107.6 °F - closed cup
• Flash Point(C): 42 °C - closed cup