91917

5,5,5-Trifluoro-DL-leucine

≥98.0% (sum of isomers, HPLC)

• Synonym(s): (±)-2-Amino-4-(trifluoromethyl)pentanoic acid
• Empirical Formula (Hill Notation): C₆H₁₀F₃NO₂
• CAS Number: 2792-72-5
• Molecular Weight: 185.14
• MDL number: MFCD00039528
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 329770097
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥98.0% (sum of isomers, HPLC)
• form: crystals
• reaction suitability: reaction type: solution phase peptide synthesis
• application(s): peptide synthesis
• SMILES string: CC(CC(N)C(O)=O)C(F)(F)F
• InChI: 1S/C6H10F3NO2/c1-3(6(7,8)9)2-4(10)5(11)12/h3-4H,2,10H2,1H3,(H,11,12)
• InChI key: XFGVJLGVINCWDP-UHFFFAOYSA-N

Description

General description

5,5,5-Trifluoro-DL-leucine, also known as trifluoroleucine, is an analog of L-leucine amino acid, often used to synthesize highly fluorinated peptides.

Application

5,5,5-trifluoroleucine can be incorporated into the coiled-coil peptides to increase their thermal stability.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves