921947

N-Sulfinyl-O-(tert-butyl)hydroxylamine

≥95%

• Synonym(s): t-BuONSO
• Empirical Formula (Hill Notation): C₄H₉NO₂S
• CAS Number: 2567792-04-3
• Molecular Weight: 135.18
• MDL number: MFCD33021394
• UNSPSC Code: 12352116

Properties

• Quality Level: 100
• Assay: ≥95%
• form: liquid
• refractive index: n/D 1.454
• density: 1.062 g/mL
• storage temp.: −20°C
• SMILES string: [S](=NOC(C)(C)C)=O
• InChI: 1S/C4H9NO2S/c1-4(2,3)7-5-8-6/h1-3H3
• InChI key: QNDHWAYLAJVRCB-UHFFFAOYSA-N

Description

Application

t-BuONSO is a stable reagent active for the synthesis of primary sulfonamides when used in conjunction with organolithium or Grignard reagents. t-BuONSO is tolerant of a variety of alkyl and aryl substrates and can be used in the synthesis of many medicinally relevant compounds.

Other Notes

Modular Sulfondiimine Synthesis Using a Stable Sulfinylamine Reagent


Harnessing Sulfinyl Nitrenes: A Unified One-Pot Synthesis of Sulfoximines and Sulfonimidamides


Primary Sulfonamide Synthesis Using the Sulfinylamine Reagent N-Sulfinyl-O-(tert-butyl)hydroxylamine, t-BuONSO

Safety Information

• Pictograms: GHS02,GHS08
• Signal Word: Danger
• Hazard Statements: H242,H317,H334
• Precautionary Statements: P210 - P235 - P280 - P302 + P352 - P370 + P378 - P403
• Hazard Classifications: Resp. Sens. 1 - Self-react. C - Skin Sens. 1
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable