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Key Documents

924482

Sigma-Aldrich

Methacrylated Alginate

Medium Viscosity, Low endotoxin

Synonym(s):

3D Bioprinting, AlMA, AlgMA, Alginate, Methacrylate, Sodium Alginate

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

description

Degree of Substitution: 15-25%

Quality Level

form

(Powder or chunk(s) or fibers)

impurities

<10 CFU/g Bioburden (Aerobic)
<10 CFU/g Bioburden (Fungal)
<100 EU/g Endotoxin

color

white to off-white

suitability

conforms to structure for NMR

Application

This product is a low endotoxin version alginate methacrylate ready to be used in biomedical applications.
Alginate is an anionic polysaccharide that is widely used in pharmaceutical and biomedical applications due to its non-animal origin, low toxicity, biocompatibility, and biodegradability. Alginate hydrogels are commonly used to fabricate tissue engineering scaffolds, bioinks for 3D bioprinting, and nanocarriers for drug & gene delivery. Due to the thermal or photochemical crosslinking of the terminal methacrylates, methacrylate-functionalized alginate can be used to prepare hydrogels resistant to matrix degradation. Properties of the resulting hydrogel (e.g., stiffness, swelling ratio, rate of degradation) can be tuned by alginate molecular weight, degree of methacrylate functionalization, and crosslink density.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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