927457

SDASO-S crosslinker

≥95%

• Synonym(s): 2,5-Dioxopyrrolidin-1-yl 3-((2-(3-methyl-3H-diazirin-3-yl)ethyl)sulfinyl)propanoate, Succinimidyl diazirine sulfoxide
• Empirical Formula (Hill Notation): C₁₁H₁₅N₃O₅S
• Molecular Weight: 301.32
• MDL number: MFCD34704602
• UNSPSC Code: 12352106

Properties

• Quality Level: 100
• Assay: ≥95%
• form: powder
• mp: 87 °C
• storage temp.: −20°C
• SMILES string: O=C(CCS(CCC1(N=N1)C)=O)ON2C(CCC2=O)=O
• InChI: 1S/C11H15N3O5S/c1-11(12-13-11)5-7-20(18)6-4-10(17)19-14-8(15)2-3-9(14)16/h2-7H2,1H3
• InChI key: MSHAOLYSQMKWAS-UHFFFAOYSA-N

Description

Application

SDASO-S (succinimidyl diazirine sulfoxide) is mass-spectrometry cleavable heterobifunctional cross-linker, which can be used in the analysis of protein structure, or protein-protein interactions. SDASO-S is photoactivated, allowing for the first time photocross-linking of proteins, and rapid, accurate analysis by MS.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

https://www.sciencedirect.com/science/article/pii/S1535947621000578">Enabling Photoactivated Cross-Linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-Cleavable Cross-Linkers

Safety Information

• Pictograms: GHS02
• Signal Word: Danger
• Hazard Statements: H242
• Precautionary Statements: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable