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Key Documents

G6503

Sigma-Aldrich

Glycine ethyl ester hydrochloride

99%, for peptide synthesis

Synonym(s):

GEE, Ethyl glycinate hydrochloride

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About This Item

Linear Formula:
NH2CH2COOC2H5 · HCl
CAS Number:
Molecular Weight:
139.58
Beilstein:
3594034
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Product Name

Glycine ethyl ester hydrochloride, 99%

Quality Level

Assay

99%

form

powder or chunks

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

drug transporter assay: suitable

color

white

mp

145-146 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CCOC(=O)CN

InChI

1S/C4H9NO2.ClH/c1-2-7-4(6)3-5;/h2-3,5H2,1H3;1H

InChI key

TXTWXQXDMWILOF-UHFFFAOYSA-N

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Application

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-footprinting studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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