H3275

3-Hydroxy-5-methylisoxazole

≥90%

• Synonym(s): Hymexazol
• Empirical Formula (Hill Notation): C₄H₅NO₂
• CAS Number: 10004-44-1
• Molecular Weight: 99.09
• EC Number: 233-000-6
• MDL number: MFCD00144468
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654246
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥90%
• storage temp.: 2-8°C
• SMILES string: CC1=CC(=O)NO1
• InChI: 1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)
• InChI key: KGVPNLBXJKTABS-UHFFFAOYSA-N

Description

General description

3-Hydroxy-5-methylisoxazole, also known as Hymexazol, is a hydrophilic organic molecule containing both a hydroxy group and a nitrogen atom, which enable it to act as a co-hydrogelator with other components to form self-delivery supramolecular hydrogels.

Application

3-Hydroxy-5-methylisoxazole can be used as a reactant to synthesize:

• 3-Oxoisoxazole-2(3H)-carboxamides by reacting with dimethyl-carbamoyl chloride in the presence of potassium t-butoxide.
• Hydroxymethyl-2-propen-1-yl-5-methyl-3(2H)-isoxazolone via ring-opening reaction with vinyl oxirane.

Safety Information

• Pictograms: GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302,H317,H318,H361d,H411
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves