M72803

2-Methylpiperidine

98%

• Synonym(s): α-Pipecoline, 2-Pipecoline, NSC 31047, NSC 462
• Empirical Formula (Hill Notation): C₆H₁₃N
• CAS Number: 109-05-7
• Molecular Weight: 99.17
• Beilstein: 79804
• EC Number: 203-642-1
• MDL number: MFCD00005982
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897152
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.445 (lit.)
• bp: 118-119 °C/753 mmHg (lit.)
• density: 0.844 g/mL at 25 °C (lit.)
• SMILES string: CC1CCCCN1
• InChI: 1S/C6H13N/c1-6-4-2-3-5-7-6/h6-7H,2-5H2,1H3
• InChI key: NNWUEBIEOFQMSS-UHFFFAOYSA-N

Description

Application

Reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation

Reactant for synthesis of:

• Azepan-4-ones via two step [5+2] annulation
• 2-Aminobenzoxazoles
• Unsymmetrically substituted ureas
• Corticotropin-releasing factor receptor type 1 antagonists
• Gefitinib analogues with anti-tumor activity

Safety Information

• Pictograms: GHS02,GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H302,H311 + H331,H314
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 50.0 °F - closed cup
• Flash Point(C): 10 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves