N1909

1-Naphthoic acid

96%

• Synonym(s): 1-Naphthalenecarboxylic acid
• Linear Formula: C₁₀H₇CO₂H
• CAS Number: 86-55-5
• Molecular Weight: 172.18
• Beilstein: 1908896
• EC Number: 201-681-9
• MDL number: MFCD00004007
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897538
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 96%
• form: powder
• bp: 300 °C (lit.)
• mp: 157-160 °C (lit.)
• SMILES string: OC(=O)c1cccc2ccccc12
• InChI: 1S/C11H8O2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H,12,13)
• InChI key: LNETULKMXZVUST-UHFFFAOYSA-N

Description

Application

1-Naphthoic acid can be used as a reactant to prepare:

• Perinaphthenones by dehydrative annulation with alkynes in the presence of rhodium catalyst.
• Isocoumarin derivatives by reacting with 2-butyne via aerobic oxidative cyclization using Rh catalyst.
• N-Methoxy-N-methyl-1-naphthalenecarboxamide (Weinreb amide) by reacting with N,O-dimethylhydroxylamine and phosphorus trichloride.
• 1,4-Dihydro-1-naphthalenecarboxylic acid by Birch reduction.

Other Notes

Remainder 2-naphthoic acid

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves