640004P

DMABA-d4 NHS Ester

Avanti Research^™ - A Croda Brand

• Synonym(s): 4-(dimethylamino)benzoic acid N-hydroxysuccinimide ester-d4
• Empirical Formula (Hill Notation): C₁₃H₁₀D₄N₂O₄
• CAS Number: 1175002-03-5
• Molecular Weight: 266.29
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• description: 4-(dimethylamino)-2,5-dioxo-1-pyrrolidinyl ester-benzoic-2,3,5,6-d4 acid
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (640004P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CN(C)C1=C([2H])C([2H])=C(C(ON(C(CC2)=O)C2=O)=O)C([2H])=C1[2H]

Description

General description

The DMABA NHS ester reagents were developed by Dr. Robert Murphy′s laboratory at the University of Colorado in order to create PE derivatives where all subclasses and potentially oxidized products could be universally detected using a common precursor ion in the positive ion mode by Mass Spectrometry.

Biochem/physiol Actions

DMABA-d4 NHS Ester is a deuterium enriched 4-(dimethylamino)benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagent. It helps in assessing distribution of phosphatidylethanolamine in RAW 264.7 cells. DMABA-d4 NHS ester is used for derivatization studies. DMABA esters enable lipid quantification and profiling during biological events.

Deuterium enriched 4-(dimethylamino) benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagents (d0, d4, d6, d10) derivatize the primary amine group of lipids, such as glycerophosphoethanolamine (PE) lipid species.

Packaging

5 mL Amber Glass Screw Cap Vial (640004P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids