700149P

16:0 cholesteryl-d7 ester

Avanti Research^™ - A Croda Brand 700149P, powder

• Synonym(s): cholesteryl-d7 palmitate
• Empirical Formula (Hill Notation): C₄₃H₆₉D₇O₂
• CAS Number: 1416275-32-5
• Molecular Weight: 632.11
• MDL number: MFCD02063886
• UNSPSC Code: 41141804
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (700149P-10mg); pkg of 1 × 25 mg (700149P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 700149P
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.

Application

16:0 cholesteryl-d7 ester has been used:

• in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
• as an internal standard in mass spectrometry for quantification of nerve lipids from mice
• as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
• as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
• in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay

Biochem/physiol Actions

Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.

Packaging

5 mL Amber Glass Screw Cap Vial (700149P-10mg)

5 mL Amber Glass Screw Cap Vial (700149P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids