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791300P

Avanti

18:0 PE-DTPA

Avanti Research - A Croda Brand 791300P, powder

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C55H118N9O17P
CAS Number:
Molecular Weight:
1208.55
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (791300P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 791300P

shipped in

dry ice

storage temp.

−20°C

General description

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (18:0 PE-DTPA) comprises synthetic phospholipid derivative of ethanolamine.
This chelate is used for preparing MRI contrast agents.

Application

18:0 PE-DTPA (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (ammonium salt)) has been used to chelate liposome-based cationic adjuvant formulation (CAF01). It has also been used in the liposome preparation for imaging studies

Biochem/physiol Actions

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (18:0 PE-DTPA) or PE-DTPA binding and interaction with the Toll-like receptor-2 regulates immune response . PE-DTPA acts as a lipopolysaccharide antagonist and elicits rescue functionality in sepsis by blocking nuclear factor κ -light-chain-enhancer of activated B cells based transcription.

Packaging

5 mL Amber Glass Screw Cap Vial (791300P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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