810218P

C6-NBD Sphingomyelin

Avanti Research^™ - A Croda Brand 810218P, powder

• Synonym(s): N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sphingosine-1-phosphocholine
• Empirical Formula (Hill Notation): C₃₅H₆₁N₆O₉P
• CAS Number: 94885-04-8
• Molecular Weight: 740.87
• MDL number: MFCD01074983
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (810218P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810218P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](NC(=O)CCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C35H61N6O9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-21-32(42)30(28-49-51(46,47)48-27-26-41(2,3)4)37-33(43)22-19-17-20-25-36-29-23-24-31(40(44)45)35-34(29)38-50-39-35/h18,21,23-24,30,32,42H,5-17,19-20,22,25-28H2,1-4H3,(H2-,36,37,39,43,46,47)/b21-18+/t30-,32+/m0/s1
• InChI key: YDBDYTGWMRUUSN-PERJAUJZSA-N

Description

General description

Sphingomyelin is a membrane phospholipid with a central sphingosine and an amide linked fatty acid. Phosphocholine forms the polar head group. It is one of the major phospholipid present in milk fat globule membrane.

Application

C6-NBD sphingomyelin is suitable for endocytosis assay.

Biochem/physiol Actions

Sphingomyelin controls cell growth, differentiation, apoptosis and signal transduction along the membrane. It is known to prevent the proliferation of colon tumour. Sphingomyelin also inhibits cholesterol absorption. Abnormal accumulation of sphingomyelin causes Niemann Pick disease.

Packaging

5 mL Amber Glass Screw Cap Vial (810218P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable