850150P

18:1 PI(3)P

Avanti Research^™ - A Croda Brand

• Synonym(s): PIP[3′](18:1/18:1)
• Empirical Formula (Hill Notation): C₄₅H₉₀N₂O₁₆P₂
• CAS Number: 1246303-09-2
• Molecular Weight: 977.15
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′-phosphate) (ammonium salt)
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850150P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850150P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]
• InChI: 1S/C45H84O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(46)57-35-37(59-39(47)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)36-58-63(55,56)61-45-42(50)40(48)41(49)44(43(45)51)60-62(52,53)54;;/h17-20,37,40-45,48-51H,3-16,21-36H2,1-2H3,(H,55,5
• InChI key: BYXVELJOJLXSIL-ADVUQDOQSA-N

Description

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol phosphate is present in the plasma membrane.

Application

18:1 PIP has been used in liposome preparation. It may also be used to generate small unilamellar vesicles for liposome flotation assays.

Biochem/physiol Actions

Phosphatidylinositol phosphate helps to promote the plasma membrane H⁺-ATPase of Saccharomyces cerevisiae. Phosphatidylinositol 3-phosphate (PtdIns3P) is very essential for the biogenesis of autophagosomes and their precursors.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850150P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850150P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids