860540P

C8 Glucosyl(β) Ceramide (d18:1/8:0)

Avanti Research^™ - A Croda Brand 860540P, powder

• Synonym(s): D-glucosyl-β-1,1′-N-octanoyl-D-erythro-sphingosine
• Empirical Formula (Hill Notation): C₃₂H₆₁NO₈
• CAS Number: 111956-47-9
• Molecular Weight: 587.83
• MDL number: MFCD07374298
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 5 mg (860540P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860540P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
• InChI: 1S/C32H61NO8/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-26(35)25(33-28(36)22-20-17-8-6-4-2)24-40-32-31(39)30(38)29(37)27(23-34)41-32/h19,21,25-27,29-32,34-35,37-39H,3-18,20,22-24H2,1-2H3,(H,33,36)/b21-19+/t25-,26+,27?,29+,30?,31?,32+/m0/s1
• InChI key: LCEXEEHGNKGJES-LSHBQEOXSA-N

Description

General description

C8 Glucosyl(β) Ceramide (d18:1/8:0) or D-glucosyl-β-1,1′-N-octanoyl-D-erythro-sphingosine is a short-chain glycosphingolipid (SC-GSL).

Application

C8 Glucosyl(β) Ceramide (d18:1/8:0) or D-glucosyl-β-1,1′-N-octanoyl-D-erythro-sphingosine has been used as a stock solution for the in vitro treatment of bacteria and to study the role of sphingolipids on pulmonary Pseudomonas aeruginosa infections in cystic fibrosis (CF). It may be suitable for the preparation of liposomes. It may also be used as a standard for the quantification of mitoxantrone in tumor by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem/physiol Actions

C8 Glucosyl(β) Ceramide (d18:1/8:0) or D-glucosyl-β-1,1′-N-octanoyl-D-erythro-sphingosine improves intracellular drug delivery in tumor cells. It is also considered as a drug uptake enhancer.

Packaging

5 mL Amber Glass Screw Cap Vial (860540P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids