870601C

Azelaoyl-PAF

Avanti Research^™ - A Croda Brand 870601C

• Synonym(s): 1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₃₃H₆₆NO₉P
• CAS Number: 354583-69-0
• Molecular Weight: 651.85
• MDL number: MFCD03412018
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: liquid
• packaging: pkg of 1 × 1 mL (870601C-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 870601C
• concentration: 1 mg/mL (870601C-1mg)
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1
• InChI key: ZDFOCDTXDPKJKA-WJOKGBTCSA-N

Description

General description

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid.

Application

Azelaoyl-PAF may be used in binding assay of anti-inflammatory peptides, 2F and 4F.

Biochem/physiol Actions

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) acts as an agonist for peroxisome proliferator-activated receptors γ(PPAR-γ). It may be used as a therapeutic for Friedreich′s ataxia (FRDA). At low concentrations azelaoyl-PAF may induce apoptosis.

Packaging

5 mL Clear Glass Sealed Ampule (870601C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• WGK: WGK 3